Pseudoprotodioscin( —— )

Catalog No. M17757 CAS No. 102115-79-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Pseudoprotodioscin
Note

Research use only, not for human use.
Brief Description

1. Pseudoprotodioscin has moderate cytotoxicity.
Description

Pseudoprotodioscin has moderate cytotoxicity.
In Vitro

In Hep G2 cells, Pseudoprotodioscin increases ABCA1 protein and mRNA levels, and promotes the effluxion of ApoA-1-mediated cholesterol. Pseudoprotodioscin inhibits SREBP1c and SREBP2 transcription by decreasing microRNA 33a/b levels. This procedure reciprocally lead to the increase of ABCA1 levels. In THP-1 macrophages, Pseudoprotodioscin shows the similar effect, which reduces HMGCR, FAS and ACC mRNA levels and promotes low density lipoprotein receptor by decreasing the PCSK9 levels.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Others-Field
Indication

——

CAS Number

102115-79-7
Formula Weight

1031.2
Molecular Formula

C51H82O21
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : ≥ 100 mg/mL (96.98 mM)D)
SMILES

CC1C(C(C(C(O1)OC2C(OC(C(C2O)OC3C(C(C(C(O3)C)O)O)O)OC4CCC5(C6CCC7(C(C6CC=C5C4)CC8C7C(=C(O8)CCC(C)COC9C(C(C(C(O9)CO)O)O)O)C)C)C)CO)O)O)O
Chemical Name

——