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PD-1-IN-22

CAS No. 2349372-98-9

PD-1-IN-22( —— )

Catalog No. M26359 CAS No. 2349372-98-9

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 299 In Stock
2MG 166 In Stock
5MG 256 In Stock
10MG 375 In Stock
25MG 562 In Stock
50MG 776 In Stock
100MG 1042 In Stock
200MG Get Quote In Stock
500MG 2102 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    PD-1-IN-22
  • Note
    Research use only, not for human use.
  • Brief Description
    PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).
  • Description
    PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).(In Vitro):PD-1-IN-22 dose-dependently elevates interferon-γ（IFN-γ) secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells.
  • In Vitro
    PD-1-IN-22 dose-dependently elevates IFN-γ secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DGK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2349372-98-9
  • Formula Weight
    459.506
  • Molecular Formula
    C25H25N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1c(NC(=O)c2cc(CNCCO)cn3cnnc23)cccc1-c1ccc2OCCOc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Slack BE, Richardson UI, Nitsch RM, Wurtman RJ. Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line. Brain Res. 1992 Jul 10;585(1-2):169-76.
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