Cart
sales@molnova.com
DB07268
CAS No. 929007-72-7
DB07268( DB07268 | DB-07268 | DB 07268 )
Catalog No. M17669 CAS No. 929007-72-7
DB07268 is a potent and selective JNK1 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
|
| 2MG | 41 | In Stock |
|
| 5MG | 77 | In Stock |
|
| 10MG | 120 | In Stock |
|
| 25MG | 237 | In Stock |
|
| 50MG | 419 | In Stock |
|
| 100MG | 617 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDB07268
-
NoteResearch use only, not for human use.
-
Brief DescriptionDB07268 is a potent and selective JNK1 inhibitor.
-
DescriptionDB07268 is is a potent and selective JNK1 inhibitor.
-
In VitroDB07268 (Compound 2b) also inhibits CHK1, PAK4, AKT1, and ERK2 with IC50s of 0.82 μM, 5.5 μM, 15 μM, and 25 μM, respectively.
-
In Vivo——
-
SynonymsDB07268 | DB-07268 | DB 07268
-
PathwayMAPK/ERK Signaling
-
TargetERK
-
RecptorJNK1
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number929007-72-7
-
Formula Weight321.33
-
Molecular FormulaC17H15N5O2
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 32 mg/mL; 99.59 mM
-
SMILESc1cccc(c1Nc1ccnc(n1)Nc1cccc(c1)O)C(=O)N
-
Chemical Name2-((2-((3-hydroxyphenyl)amino)pyrimidin-4-yl)amino)benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Liu M, et al. Bioorg Med Chem Lett. 2007 Feb 1;17(3):668-72.
molnova catalog
related products
-
GDC-0994
GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.
-
CAFESTOL
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells.?Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.
-
ZINC12409120
ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23:α-Klotho interaction.
