S107

CAS No. 927871-76-9

S107( —— )

Catalog No. M17667 CAS No. 927871-76-9

S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 61 In Stock
2MG 30 In Stock
5MG 55 In Stock
10MG 84 In Stock
25MG 152 In Stock
50MG 249 In Stock
100MG 355 In Stock
200MG 505 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    S107
  • Note
    Research use only, not for human use.
  • Brief Description
    S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
  • Description
    S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    927871-76-9
  • Formula Weight
    209.31
  • Molecular Formula
    C11H15NOS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 38 mg/mL; 181.55 mM
  • SMILES
    CN1CCSc2c(C1)cc(cc2)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lehnart SE, et al. J Clin Invest. 2008 Jun;118(6):2230-45.
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