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4-Oxofenretinide
CAS No. 865536-65-8
4-Oxofenretinide( 4-Oxo-4-HPR | 4-Oxo Fenretinide | 4-Keto-4-HPR )
Catalog No. M17628 CAS No. 865536-65-8
4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 45 | In Stock |
|
| 5MG | 65 | In Stock |
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| 10MG | 104 | In Stock |
|
| 25MG | 185 | In Stock |
|
| 50MG | 277 | In Stock |
|
| 100MG | 500 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name4-Oxofenretinide
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NoteResearch use only, not for human use.
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Brief Description4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.
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Description4-Oxo-4-HPR is an inhibitor of tubulin polymerization, inducing marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. It is also a fenretinide metabolite.
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In Vitro——
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In Vivo——
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Synonyms4-Oxo-4-HPR | 4-Oxo Fenretinide | 4-Keto-4-HPR
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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Recptorcell cycle arrest and apoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number865536-65-8
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Formula Weight405.53
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Molecular FormulaC26H31NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=C(C(CCC1=O)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)Nc1ccc(cc1)O)/C)/C
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Chemical Name(2E,4E,6E,8E)-N-(4-Hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Villani MG,et al. Cancer Res. 2006 Mar 15;66(6):3238-47.
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