Tedizolid Phosphate

Research use only, not for human use.

Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.

Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.(In Vitro):Tedizolid phosphate (TR-701FA; 0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.(In Vivo):For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate (TR-701FA) at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.

Tedizolid phosphate (TR-701FA; 0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.

For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate (TR-701FA) at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.

TR-701FA

Immunology/Inflammation

Amino Acids and Derivatives

Others

Infection

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856867-55-5

450.32

C17H16FN6O6P

>98% (HPLC)

DMSO : ≥ 36 mg/mL. 79.94 mM. H2O : 0.1 mg/mL0.22 mM;

CN1N=NC(=N1)C1=NC=C(C=C1)C1=CC=C(C=C1F)N1C[C@H](COP(O)(O)=O)OC1=O

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(-20℃)

With Ice Pack

≥ 2 years