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Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - Syk Inhibitor II

Syk Inhibitor II

CAS No. 726695-51-8

Syk Inhibitor II( —— )

Catalog No. M17582 CAS No. 726695-51-8

Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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1 mL x 10 mM in DMSO 82 In Stock
5MG 60 In Stock
10MG 113 In Stock
50MG 295 In Stock
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Biological Information

  • Product Name
    Syk Inhibitor II
  • Note
    Research use only, not for human use.
  • Brief Description
    Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
  • Description
    Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    Syk
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    726695-51-8
  • Formula Weight
    340.3
  • Molecular Formula
    C14H15F3N6O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (14.69 mM)
  • SMILES
    NCCNC1=NC(NC2=CC(C(F)(F)F)=CC=C2)=C(C(N)=O)C=N1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hisamichi H,etal.Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives.Bioorg Med Chem. 2005 Aug 15;13(16):4936-51.
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