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NITD-2

CAS No. 1197896-79-9

NITD-2( —— )

Catalog No. M23369 CAS No. 1197896-79-9

NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	188	In Stock
5MG	170	In Stock
10MG	275	In Stock
25MG	471	In Stock
50MG	641	In Stock
100MG	923	In Stock
200MG	1237	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

NITD-2
Note

Research use only, not for human use.
Brief Description

NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.
Description

NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.
In Vitro

NITD-2 inhibits de novo RNA synthesis.NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration.
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

RNA Synthesis
Research Area

——
Indication

——

Chemical Information

CAS Number

1197896-79-9
Formula Weight

433.48
Molecular Formula

C23H19N3O4S
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

O=C(O)C1=CC=CC=C1NS(=O)(C2=CC=CC(C3=CN(CC4=CC=CC=C4)N=C3)=C2)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.

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