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TTNPB
CAS No. 71441-28-6
TTNPB( TTNPB | Ro 13-7410 | Ro-13-7410 | Arotinoid acid )
Catalog No. M17576 CAS No. 71441-28-6
TTNPB, a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM), respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
|
| 2MG | 31 | In Stock |
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| 5MG | 49 | In Stock |
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| 10MG | 75 | In Stock |
|
| 25MG | 157 | In Stock |
|
| 50MG | 300 | In Stock |
|
| 100MG | 454 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 986 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTTNPB
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NoteResearch use only, not for human use.
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Brief DescriptionTTNPB, a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM), respectively.
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DescriptionTTNPB is a selective and highly potent agonist of retinoic acid receptors (RAR) α, β, and γ.
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In Vitro——
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In Vivo——
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SynonymsTTNPB | Ro 13-7410 | Ro-13-7410 | Arotinoid acid
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorRARα| RARβ| RARγ| RARγ
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number71441-28-6
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Formula Weight348.48
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Molecular FormulaC24H28O2
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Purity>98% (HPLC)
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SolubilityDMSO : 11.25 mg/mL. 32.28 mM;
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SMILESc12c(C(CCC2(C)C)(C)C)ccc(c1)/C(=C/c1ccc(cc1)C(=O)O)/C
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Chemical Name4-[(E)-2-(5,5,8,8-Tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pignatello MA, et al. Toxicol Appl Pharmacol. 1997, 142(2), 319-327.
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