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Home - Products - Metabolic Enzyme/Protease - P450 - NSC 207895

NSC 207895

CAS No. 58131-57-0

NSC 207895( —— )

Catalog No. M17547 CAS No. 58131-57-0

NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 110 In Stock
2MG 70 In Stock
5MG 116 In Stock
10MG 187 In Stock
25MG 432 In Stock
50MG 625 In Stock
100MG 889 In Stock
200MG Get Quote In Stock
500MG 1786 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    NSC 207895
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
  • Description
    NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
  • In Vitro
    Western Blot Analysis Cell Line:RAW 264.7 cells.Concentration:0.5 μM.Incubation Time:30 min (stimulated with LPS (100 ng/ml) for 6 h).Result:Upregulated p53 protein levels.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    p53 , MDMX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    58131-57-0
  • Formula Weight
    279.25
  • Molecular Formula
    C11H13N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 31.25 mg/mL (111.91 mM)
  • SMILES
    CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang H, et al. Mol Cancer Ther, 2011, 10(1), 69-79.
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