SBC-110736
CAS No. 1629166-02-4
SBC-110736( SBC-110736 | SBC 110736 | SBC110736 )
Catalog No. M17349 CAS No. 1629166-02-4
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 123 | In Stock |
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| 25MG | 246 | In Stock |
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| 50MG | 362 | In Stock |
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| 100MG | 606 | In Stock |
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| 200MG | 849 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSBC-110736
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NoteResearch use only, not for human use.
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Brief DescriptionSBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor.
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DescriptionSBC-110736 is a novel inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), and has been shown to lower cholesterol levels in mice.
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In Vitro——
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In VivoSBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels.
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SynonymsSBC-110736 | SBC 110736 | SBC110736
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PathwayNeuroscience
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TargetGluR
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RecptorPCSK9
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number1629166-02-4
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Formula Weight413.51
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Molecular FormulaC26H27N3O2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL. 241.83 mM
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SMILESO=C(c1ccc(NC(C)=O)cc1)N3CCN(CC3c2ccccc2)c4ccc(C)cc4
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Chemical NameN-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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S-(4-Hydroxybenzyl)g...
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
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S 18986
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