SBC-110736

CAS No. 1629166-02-4

SBC-110736( SBC-110736 | SBC 110736 | SBC110736 )

Catalog No. M17349 CAS No. 1629166-02-4

SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 85 In Stock
5MG 77 In Stock
10MG 123 In Stock
25MG 246 In Stock
50MG 362 In Stock
100MG 606 In Stock
200MG 849 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SBC-110736
  • Note
    Research use only, not for human use.
  • Brief Description
    SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor.
  • Description
    SBC-110736 is a novel inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), and has been shown to lower cholesterol levels in mice.
  • In Vitro
    ——
  • In Vivo
    SBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels.
  • Synonyms
    SBC-110736 | SBC 110736 | SBC110736
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    PCSK9
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1629166-02-4
  • Formula Weight
    413.51
  • Molecular Formula
    C26H27N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 100 mg/mL. 241.83 mM
  • SMILES
    O=C(c1ccc(NC(C)=O)cc1)N3CCN(CC3c2ccccc2)c4ccc(C)cc4
  • Chemical Name
    N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. WO2014150395A1
molnova catalog
related products
  • ABP688

    ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.

  • PD168393

    PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.

  • (S)-MCPG

    (S)-MCPG ((+)-MCPG) is a class I/II metabotropic glutamate receptors (mGluRs) antagonist that blocks spatial learning and long-term enhancement of the dentate gyrus in vivo in rats, and can be used to study neurological disorders.