SBC-110736
CAS No. 1629166-02-4
SBC-110736( SBC-110736 | SBC 110736 | SBC110736 )
Catalog No. M17349 CAS No. 1629166-02-4
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 60 | In Stock |
|
| 5MG | 96 | In Stock |
|
| 10MG | 159 | In Stock |
|
| 25MG | 339 | In Stock |
|
| 50MG | 506 | In Stock |
|
| 100MG | 711 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSBC-110736
-
NoteResearch use only, not for human use.
-
Brief DescriptionSBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor.
-
DescriptionSBC-110736 is a novel inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), and has been shown to lower cholesterol levels in mice.
-
In Vitro——
-
In VivoSBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels.
-
SynonymsSBC-110736 | SBC 110736 | SBC110736
-
PathwayNeuroscience
-
TargetGluR
-
RecptorPCSK9
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number1629166-02-4
-
Formula Weight413.51
-
Molecular FormulaC26H27N3O2
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 100 mg/mL. 241.83 mM
-
SMILESO=C(c1ccc(NC(C)=O)cc1)N3CCN(CC3c2ccccc2)c4ccc(C)cc4
-
Chemical NameN-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. WO2014150395A1
molnova catalog
related products
-
VU0155094
ML397 is a positive allosteric modulator with differential activity at the various group III mGluRs.
-
S-(4-Hydroxybenzyl)g...
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
-
MTEP hydrochloride
MTEP hydrochloride is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM respectively).
Cart
sales@molnova.com