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GSK2830371

CAS No. 1404456-53-6

GSK2830371( GSK 2830371 | GSK2830371 | GSK-2830371 )

Catalog No. M17279 CAS No. 1404456-53-6

GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 46 In Stock
5MG 46 In Stock
10MG 78 In Stock
25MG 145 In Stock
50MG 248 In Stock
100MG 416 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    GSK2830371
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.
  • Description
    GSK 2830371 is a WiP1 inhibitor. It inhibits cell growth and tumor growth in lymphoma and neuroblastoma models.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    GSK 2830371 | GSK2830371 | GSK-2830371
  • Pathway
    Angiogenesis
  • Target
    FGFR
  • Recptor
    Wip1 phosphatase
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1404456-53-6
  • Formula Weight
    461.02
  • Molecular Formula
    C23H29ClN4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 51 mg/mL. 110.62 mM
  • SMILES
    CC1=NC=C(Cl)C=C1NCC1=CC=C(S1)C(=O)N[C@@H](CC1CCCC1)C(=O)NC1CC1
  • Chemical Name
    (S)-5-(((5-chloro-2-methylpyridin-3-yl)amino)methyl)-N-(3-cyclopentyl-1-(cyclopropylamino)-1-oxopropan-2-yl)thiophene-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gilmartin AG, et al. Nat Chem Biol. 2014, 10(3), 181-187
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