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UNC0631
CAS No. 1320288-19-4
UNC0631( UNC0631, UNC 0631, UNC-0631 )
Catalog No. M17245 CAS No. 1320288-19-4
UNC0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 93 | In Stock |
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| 10MG | 148 | In Stock |
|
| 25MG | 297 | In Stock |
|
| 50MG | 458 | In Stock |
|
| 100MG | 668 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUNC0631
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NoteResearch use only, not for human use.
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Brief DescriptionUNC0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).
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DescriptionUNC-0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53.
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In Vitro——
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In Vivo——
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SynonymsUNC0631, UNC 0631, UNC-0631
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PathwayAngiogenesis
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TargetEGFR
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RecptorG9a
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number1320288-19-4
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Formula Weight635.93
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Molecular FormulaC37H61N7O2
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Purity>98% (HPLC)
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SolubilityDMSO : 16.67 mg/mL. 26.21 mM; H2O : < 0.1 mg/mL
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SMILESCOc1c(OCCCN2CCCCC2)cc2nc(nc(NC3CCN(CC4CCCCC4)CC3)c2c1)N1CCCN(CC1)C(C)C
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Chemical NameN-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Liu F, et al. J Med Chem. 2011, 54(17), 6139-6150.
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