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Home - Products - Cytoskeleton/Cell Adhesion Molecules - Microtubule/Tubulin - VU 0364439

VU 0364439

CAS No. 1246086-78-1

VU 0364439( VU0364439, VU-0364439, VU 0364439 )

Catalog No. M17215 CAS No. 1246086-78-1

VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 81 In Stock
5MG 73 In Stock
10MG 117 In Stock
25MG 211 In Stock
50MG 330 In Stock
100MG 529 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    VU 0364439
  • Note
    Research use only, not for human use.
  • Brief Description
    VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
  • Description
    VU0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VU0364439, VU-0364439, VU 0364439
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    mGluR4
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1246086-78-1
  • Formula Weight
    422.29
  • Molecular Formula
    C18H13Cl2N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL. 118.40 mM;
  • SMILES
    c1ccc(c(c1)NS(=O)(=O)c1c(cc(cc1)NC(=O)c1ccccn1)Cl)Cl
  • Chemical Name
    N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Engers DW, et al. Bioorg Med Chem Lett, 2010, 20(17), 5175-5178.
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