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VU 0364439
CAS No. 1246086-78-1
VU 0364439( VU0364439, VU-0364439, VU 0364439 )
Catalog No. M17215 CAS No. 1246086-78-1
VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 81 | In Stock |
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| 5MG | 73 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 211 | In Stock |
|
| 50MG | 330 | In Stock |
|
| 100MG | 529 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVU 0364439
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NoteResearch use only, not for human use.
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Brief DescriptionVU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
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DescriptionVU0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
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In Vitro——
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In Vivo——
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SynonymsVU0364439, VU-0364439, VU 0364439
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptormGluR4
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1246086-78-1
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Formula Weight422.29
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Molecular FormulaC18H13Cl2N3O3S
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Purity>98% (HPLC)
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SolubilityDMSO : 50 mg/mL. 118.40 mM;
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SMILESc1ccc(c(c1)NS(=O)(=O)c1c(cc(cc1)NC(=O)c1ccccn1)Cl)Cl
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Chemical NameN-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Engers DW, et al. Bioorg Med Chem Lett, 2010, 20(17), 5175-5178.
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