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GSK3011724A

CAS No. ——

GSK3011724A( DG167 | GSK-3011724A )

Catalog No. M17106 CAS No. ——

GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

GSK3011724A
Note

Research use only, not for human use.
Brief Description

GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM).
Description

GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM), shows anti-tubercular activity (MIC H37Rv=0.8 uM); shows much weaker apparent dissociation constant for both Pks10 and Pks (Kd=1.4 uM); inhibits mycolic acid biosynthesis and shows negligible activity against a panel of unrelated proteins and 18 Gram-positive and Gram-negative bacterial species.
In Vitro

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In Vivo

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Synonyms

DG167 | GSK-3011724A
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

——
Formula Weight

267.347
Molecular Formula

C12H17N3O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

N-(1-methyl-1H-indazol-6-yl)butane-1-sulfonamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kumar P, et al. MBio. 2018 Dec 18;9(6). pii: e02101-17. 2. Abrahams KA, et al. Nat Commun. 2016 Sep 1;7:12581.

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