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J8-C8
CAS No. 1150565-77-7
J8-C8( acyl-HSLs inhibitor J8-C8 )
Catalog No. M10530 CAS No. 1150565-77-7
J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameJ8-C8
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NoteResearch use only, not for human use.
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Brief DescriptionJ8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
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DescriptionJ8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production; inhibits C8-HSL synthesis in a dose-dependent manner; a new class of quorum sensing (QS)-inhibiting therapeutic agents.
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In Vitro——
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In Vivo——
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Synonymsacyl-HSLs inhibitor J8-C8
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number1150565-77-7
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Formula Weight237.343
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Molecular FormulaC14H23NO2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-(3-oxocyclohex-1-en-1-yl)octanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chung J, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12089-94.
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