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TP-238
CAS No. ——
TP-238( TP238 )
Catalog No. M17062 CAS No. ——
TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameTP-238
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NoteResearch use only, not for human use.
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Brief DescriptionTP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay.
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DescriptionTP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay, KD of 10nM for CECR2 and 120nM for BPTF in ITC assays; TP-238 has been profiled against the panel of 338 kinases and showed no activity at 1 uM, the closest off-target bromodomain inhibition is BRD9 with IC50 of 1.4 uM.
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In Vitro——
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In Vivo——
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SynonymsTP238
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight458.581
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Molecular FormulaC22H30N6O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C1=NC(C2=CC=C(OCCCN(C)C)C=C2)=CC(NCCCN3N=CC=C3)=N1)(C)=O
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Chemical NameN-(3-(1H-pyrazol-1-yl)propyl)-6-(4-(3-(dimethylamino)propoxy)phenyl)-2-(methylsulfonyl)pyrimidin-4-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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