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HDAC6 inhibitor NCT-14b
CAS No. ——
HDAC6 inhibitor NCT-14b( NCT-14b )
Catalog No. M17048 CAS No. ——
A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameHDAC6 inhibitor NCT-14b
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
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DescriptionA potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
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In Vitro——
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In Vivo——
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SynonymsNCT-14b
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight465.693
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Molecular FormulaC26H43NO4S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(S)-S-7-(adamant-1-ylamino)-6-(tert-butoxycarbonyl)-7-oxoheptyl-2-methylpropanethioate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Matsuba S, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):510-8.
2. Itoh Y, et al. J Med Chem. 2007 Nov 1;50(22):5425-38.
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