Cart
sales@molnova.com
HDAC6 inhibitor NCT-14b
CAS No. ——
HDAC6 inhibitor NCT-14b( NCT-14b )
Catalog No. M17048 CAS No. ——
A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameHDAC6 inhibitor NCT-14b
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
-
DescriptionA potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
-
In Vitro——
-
In Vivo——
-
SynonymsNCT-14b
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight465.693
-
Molecular FormulaC26H43NO4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name(S)-S-7-(adamant-1-ylamino)-6-(tert-butoxycarbonyl)-7-oxoheptyl-2-methylpropanethioate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Matsuba S, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):510-8.
2. Itoh Y, et al. J Med Chem. 2007 Nov 1;50(22):5425-38.
molnova catalog
related products
-
CHR-3996
CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3.
-
Resminostat hydrochl...
A potent inhibitor of HDAC1/3/6 with IC50s of 43-72 nM; induces hyperacetylation of histone H4 and apoptosis in MM cell lines (IC50=2.5-3 uM).
-
Belinostat
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
