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1-AM
CAS No. ——
1-AM( KRAS G12C inhibitor 1 AM )
Catalog No. M16990 CAS No. ——
A potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product Name1-AM
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.
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DescriptionA potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.
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In Vitro——
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In Vivo——
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SynonymsKRAS G12C inhibitor 1 AM
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PathwayMAPK/ERK Signaling
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TargetRas
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RecptorRas
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight510.998
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Molecular FormulaC26H28ClFN6O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3-((4-(4-acryloylpiperazin-1-yl)-6-chloro-7-(2-fluorophenyl)quinazolin-2-yl)amino)-N,N-dimethylpropanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zeng M, et al. Cell Chem Biol. 2017 Aug 17;24(8):1005-1016.e3.
molnova catalog
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