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BI605906
CAS No. 960293-88-3
BI605906( BI-605906 )
Catalog No. M16854 CAS No. 960293-88-3
BI605906 is a potent, specific IKKβ inhibitor with IC50 of 380 nM (0.1 mM ATP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 81 | In Stock |
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| 5MG | 73 | In Stock |
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| 10MG | 123 | In Stock |
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| 25MG | 254 | In Stock |
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| 50MG | 431 | In Stock |
|
| 100MG | 732 | In Stock |
|
| 200MG | 995 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBI605906
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NoteResearch use only, not for human use.
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Brief DescriptionBI605906 is a potent, specific IKKβ inhibitor with IC50 of 380 nM (0.1 mM ATP).
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DescriptionBI605906 is a potent, specific IKKβ inhibitor with IC50 of 380 nM (0.1 mM ATP), does not suppress signaling downstream of mTOR or activate AMPK; inhibits TNF-α-dependent IκB degradation and expression of proinflammatory mediators interleukin-6, interleukin-1β, and CXCL1/2 in vivol; partially inhibits the IL-1-stimulated activation of IKKε/TBK1.
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In Vitro——
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In Vivo——
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SynonymsBI-605906
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PathwayImmunology/Inflammation
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TargetIκB kinase (IKK)
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RecptorIκB kinase (IKK)
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number960293-88-3
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Formula Weight432.5084
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Molecular FormulaC17H22F2N4O3S2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 29 mg/mL
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SMILESO=C(C1=C(N)C2=C(C(F)(F)CC)C=C(N3CCC(S(=O)(C)=O)CC3)N=C2S1)N
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Chemical NameThieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Clark K, et al. Biochem J. 2011 Feb 15;434(1):93-104.
2. Cameron AR, et al. Circ Res. 2016 Aug 19;119(5):652-65.
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