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A-836339
CAS No. 959746-77-1
A-836339( A836339 )
Catalog No. M16849 CAS No. 959746-77-1
A-836339 (A836339) is a potent and selective cannabinoid CB2 receptor agonist with Ki of 0.64 and 0.76 nM for human and rat CB2 receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 57 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 62 | In Stock |
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| 10MG | 111 | In Stock |
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| 25MG | 187 | In Stock |
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| 50MG | 269 | In Stock |
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| 100MG | 382 | In Stock |
|
| 200MG | 516 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameA-836339
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NoteResearch use only, not for human use.
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Brief DescriptionA-836339 (A836339) is a potent and selective cannabinoid CB2 receptor agonist with Ki of 0.64 and 0.76 nM for human and rat CB2 receptors.
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DescriptionA-836339 (A836339) is a potent and selective cannabinoid CB2 receptor agonist with Ki of 0.64 and 0.76 nM for human and rat CB2 receptors, displays 425- and 189-fold selectivity over CB1 receptor, respectively; exhibits full agonist efficacy (Emax=102%) with high potency (EC50=1.6 nM), greater potency than other CB2-selective ligands including JWH-015 and GW-842166X; exhibits a potent CB2 receptor-mediated antihyperalgesic effect in various animal pain models, also demonstrates efficacies in the chronic constrain injury (CCI) model of neuropathic pain.
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In Vitro——
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In Vivo——
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SynonymsA836339
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number959746-77-1
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Formula Weight310.4548
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Molecular FormulaC16H26N2O2S
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Purity>98% (HPLC)
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SolubilityDMSO: 12 mg/mL
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SMILESCC1=C(C)N(CCOC)/C(S1)=N/C(C2C(C)(C)C2(C)C)=O
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Chemical NameCyclopropanecarboxamide, N-[3-(2-methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethyl-, [N(Z)]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yao BB, et al. J Pharmacol Exp Ther. 2009 Jan;328(1):141-51.
2. McGaraughty S, et al. Neuroscience. 2009 Feb 18;158(4):1652-61.
3. Hsieh GC, et al. Br J Pharmacol. 2011 Jan;162(2):428-40.
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