Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Cannabinoid Receptor - AM-630

AM-630

CAS No. 164178-33-0

AM-630( AM 630 | AM630 | 6-Iodopravodoline )

Catalog No. M12488 CAS No. 164178-33-0

A potent and selective inverse agonist for the cannabinoid receptor CB2 with Ki of 32.1 nM, 165-fold selectivity over CB1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 60 In Stock
10MG 87 In Stock
25MG 199 In Stock
50MG 327 In Stock
100MG 520 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    AM-630
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective inverse agonist for the cannabinoid receptor CB2 with Ki of 32.1 nM, 165-fold selectivity over CB1.
  • Description
    A potent and selective inverse agonist for the cannabinoid receptor CB2 with Ki of 32.1 nM, 165-fold selectivity over CB1; inhibits forskolin-stimulated cyclic AMP production in CB1-transfected cells (22.6% at 1 uM and 45.9% at 10 uM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AM 630 | AM630 | 6-Iodopravodoline
  • Pathway
    GPCR/G Protein
  • Target
    Cannabinoid Receptor
  • Recptor
    Cannabinoid Receptor
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    164178-33-0
  • Formula Weight
    504.4
  • Molecular Formula
    C23H25IN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=C(C)N(CCN2CCOCC2)C3=C1C=CC(I)=C3)C4=CC=C(OC)C=C4
  • Chemical Name
    [6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)-methanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ross RA, et al. Br J Pharmacol. 1999 Feb;126(3):665-72. 2. Malan TP Jr, et al. Pain. 2001 Sep;93(3):239-45.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • GAT-100

    GAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM.

  • JHU 75528

    JHU 75528 (JHU-75528) is a novel PET tracer with inhibitory effects on CB that can be used to study the cannabinoid system in schizophrenic patients.

  • GW405833 hydrochlori...

    A potent, selective cannabinoid receptor CB2 agonist with Ki of 3.6 nM, 1200-fold selectivity over CB1.

Sign In Join Free