Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Cannabinoid Receptor - JTE907

JTE907

CAS No. 282089-49-0

JTE907( JTE-907 | JTE 907 )

Catalog No. M13857 CAS No. 282089-49-0

A potent, selective, orally active cannabinoid CB2 receptor inverse agonist with Ki of 35.9, 1.55 and 0.38 nM for human, mouse and rat CB2, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 145 In Stock
5MG 122 In Stock
10MG 187 In Stock
25MG 330 In Stock
50MG 480 In Stock
100MG 684 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    JTE907
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective, orally active cannabinoid CB2 receptor inverse agonist with Ki of 35.9, 1.55 and 0.38 nM for human, mouse and rat CB2, respectively.
  • Description
    A potent, selective, orally active cannabinoid CB2 receptor inverse agonist with Ki of 35.9, 1.55 and 0.38 nM for human, mouse and rat CB2, respectively; increases of forskolin-stimulated cAMP production in CHO cells expressing CB2 in vitro, inhibits carrageenin-induced mouse paw edema dose dependently in mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    JTE-907 | JTE 907
  • Pathway
    GPCR/G Protein
  • Target
    Cannabinoid Receptor
  • Recptor
    Cannabinoid Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    282089-49-0
  • Formula Weight
    438.48
  • Molecular Formula
    C24H26N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (285.08 mM)
  • SMILES
    O=C(C1=CC2=C(NC1=O)C(OCCCCC)=C(OC)C=C2)NCC3=CC=C(OCO4)C4=C3
  • Chemical Name
    N-(1,3-Benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-quinolinecarboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Iwamura H, et al. J Pharmacol Exp Ther. 2001 Feb;296(2):420-5. 2. Ueda Y, et al. Eur J Pharmacol. 2005 Sep 27;520(1-3):164-71. 3. Maekawa T, et al. Eur J Pharmacol. 2006 Aug 7;542(1-3):179-83.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • GW 405833

    GW 405833 is an agonist of cannabinoid-2 (CB(2)) receptor-selective.

  • Hemopressin (human, ...

    Bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. Ki values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB1 receptor inverse agonist. Displays antinociceptive activity in vivo.

  • CB2 modulator 1

    CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.

Sign In Join Free