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Pimelic Diphenylamide 106
CAS No. 937039-45-7
Pimelic Diphenylamide 106( RGFA-8 | TC-H 106 | BRD-4657 )
Catalog No. M16712 CAS No. 937039-45-7
A slow, tight-binding inhibitor of class I HDACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 37 | In Stock |
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| 25MG | 65 | In Stock |
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| 50MG | 110 | In Stock |
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| 100MG | 200 | In Stock |
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| 200MG | 296 | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePimelic Diphenylamide 106
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NoteResearch use only, not for human use.
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Brief DescriptionA slow, tight-binding inhibitor of class I HDACs.
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DescriptionA slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively); shows weak inhibition on HDAC8 (IC50=5 uM); has preference toward HDAC3.
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In Vitro——
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In Vivo——
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SynonymsRGFA-8 | TC-H 106 | BRD-4657
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number937039-45-7
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Formula Weight339.4314
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Molecular FormulaC20H25N3O2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 25 mg/mL
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SMILESO=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=C(C)C=C2)=O
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Chemical NameHeptanediamide, N1-(2-aminophenyl)-N7-(4-methylphenyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chou CJ, et al. J Biol Chem. 2008 Dec 19;283(51):35402-9.
2. Xu C, et al. Chem Biol. 2009 Sep 25;16(9):980-9.
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