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R-999636
CAS No. 90833-53-7
R-999636( R999636 )
Catalog No. M16529 CAS No. 90833-53-7
R-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameR-999636
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NoteResearch use only, not for human use.
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Brief DescriptionR-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay.
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DescriptionR-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay; displays 5.8-fold and 7.8-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
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In Vitro——
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In Vivo——
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SynonymsR999636
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PathwayWnt/Notch/Hedgehog
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TargetBeta-catenin
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RecptorBeta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number90833-53-7
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Formula Weight395.239
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Molecular FormulaC21H12Cl2N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=CC(=CC=C1C2=NC3=C(C=C(C=C3)C(=O)O)N=C2C4=CC=C(C=C4)Cl)Cl
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Chemical Name2,3-bis(4-chlorophenyl)quinoxaline-6-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.
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