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R-360163
CAS No. 883791-50-2
R-360163( R360163 )
Catalog No. M16403 CAS No. 883791-50-2
R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameR-360163
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NoteResearch use only, not for human use.
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Brief DescriptionR-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay.
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DescriptionR-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay; displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
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In Vitro——
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In Vivo——
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SynonymsR360163
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PathwayWnt/Notch/Hedgehog
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TargetBeta-catenin
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RecptorBeta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number883791-50-2
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Formula Weight392.371
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Molecular FormulaC20H16N4O5
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(Z)-3-(2-(2-(1-allyl-2-oxoindolin-3-ylidene)hydrazinyl)-2-oxoacetamido)benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.
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