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USP10-IN-3
CAS No. 904448-58-4
USP10-IN-3( —— )
Catalog No. M16503 CAS No. 904448-58-4
USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameUSP10-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionUSP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
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DescriptionUSP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorDUB
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Research Area——
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Indication——
Chemical Information
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CAS Number904448-58-4
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Formula Weight401.979
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Molecular FormulaC23H32ClN3O
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCN(CCC)CCCNC(=O)C1=CC2=C(C=C1)C(=C3CCCCC3=N2)Cl
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Chemical Name9-chloro-N-(3-(dipropylamino)propyl)-5,6,7,8-tetrahydroacridine-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215.
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