Cart
sales@molnova.com
USP10-IN-3
CAS No. 904448-58-4
USP10-IN-3( —— )
Catalog No. M16503 CAS No. 904448-58-4
USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameUSP10-IN-3
-
NoteResearch use only, not for human use.
-
Brief DescriptionUSP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
-
DescriptionUSP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayProteasome/Ubiquitin
-
TargetDUB
-
RecptorDUB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number904448-58-4
-
Formula Weight401.979
-
Molecular FormulaC23H32ClN3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCCN(CCC)CCCNC(=O)C1=CC2=C(C=C1)C(=C3CCCCC3=N2)Cl
-
Chemical Name9-chloro-N-(3-(dipropylamino)propyl)-5,6,7,8-tetrahydroacridine-3-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215.
molnova catalog
related products
-
OTUB1/USP8-IN-1
OTUB1/USP8-IN-1 is a potent OTUB1/USP8 inhibitor with potential anticancer activity, demonstrating IC50 values of 0.17 nM for OTUB1 and 0.28 nM for USP8.
-
USP7-IN-4
(R)-USP-IN-4 is a highly potent, selective, allosteric USP7 inhibitor with IC50 of 6 nM in FP assays.
-
NSC112200
NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2.
