Walrycin-B( Walrycin B )

Catalog No. M16377 CAS No. 878419-78-4

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Product Name

Walrycin-B
Note

Research use only, not for human use.
Brief Description

A novel baterial WalR response regulator; simultaneously affects the expression of WalR regulon genes.
Description

A novel baterial WalR response regulator; simultaneously affects the expression of WalR regulon genes, leading to phenotypes consistent with those of cells starved for the WalK/WalR system and having a bactericidal effect; shows MICs of 0.39 mg/mL and 3.13 mg/mL against B. subtilis 168 and S. aureus N315, respectively.
In Vitro

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In Vivo

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Synonyms

Walrycin B
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

bacterialWalRresponseregulator
Research Area

Infection
Indication

——

CAS Number

878419-78-4
Formula Weight

337.2567
Molecular Formula

C14H10F3N5O2
Purity

>98% (HPLC)
Solubility

DMSO: 11.5 mg/mL
SMILES

O=C(C1=NC(C2=CC=C(C(F)(F)F)C=C2)=NN(C)C1=N3)N(C)C3=O
Chemical Name

Pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione, 1,6-dimethyl-3-[4-(trifluoromethyl)phenyl]-

1. Gotoh Y, et al. J Antibiot (Tokyo). 2010 Mar;63(3):127-34.

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