Rosoxacin

Research use only, not for human use.

Rosoxacin shows antibacterial activities against a broad spectrum of Gram-negative bacteria including Neisseria gonorrhoeae (MIC90 = 0.03mg/ml).

Rosoxacin shows antibacterial activities against a broad spectrum of Gram-negative bacteria including Neisseria gonorrhoeae (MIC90 = 0.03mg/ml).

Rosoxacin (0.03-8 μg/mL; 24 h) shows good susceptibilities to 32 strains of N. gonorrhoeae, with MIC range of 0.03-0.125 μg/mL.Rosoxacin (0.03-8 μg/mL; 48 h) shows antibacterial activity to C. trachomatis (11 strains), with MICs are 5 μg/mL.Rosoxacin (0.03-8 μg/mL; 6 days) shows antibacterial activity to U. urealyticum (7 strains), with MIC range of 2-8 μg/mL. Cell Viability AssayCell Line:N. gonorrhoeae (32 strains)Concentration: 0.03-8 μg/mL Incubation Time:24 hResult:Exhibited good activity of anti-N. gonorrhoeae, with MICs for 50% (among 32 strains) strains of 0.03 μg/mL, and 0.06 μg/mL for 90%.Cell Viability Assay Cell Line:C. trachomatis (11 strains)Concentration:0.03-8 μg/mL Incubation Time:48 h Result:Inhibited 11 strains of C. trachomatis with MICs were 5 μg/mL.Cell Viability Assay Cell Line:U. urealyticum (7 strains)Concentration:0.03-8 μg/mL Incubation Time:6 days Result:Inhibited 7 strains of U. urealyticum with MIC range of 2-8 μg/mL.

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Acrosoxacin

GPCR/G Protein

Antibacterial

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40034-42-2

294.31

C17H14N2O3

>98% (HPLC)

In Vitro:?DMSO : 20.83 mg/mL (70.78 mM)

CCn1cc(C(O)=O)c(=O)c2ccc(cc12)-c1ccncc1

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(-20℃)

With Ice Pack

≥ 2 years