BI 207524

CAS No. 874675-53-3

BI 207524( BI207524 )

Catalog No. M16359 CAS No. 874675-53-3

BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 1593 Get Quote
50MG 3222 Get Quote
100MG 4410 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    BI 207524
  • Note
    Research use only, not for human use.
  • Brief Description
    BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.
  • Description
    BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BI207524
  • Pathway
    Microbiology/Virology
  • Target
    HCV
  • Recptor
    HCV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    874675-53-3
  • Formula Weight
    642.153
  • Molecular Formula
    C35H36ClN5O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (E)-3-{4-[(1-{[2-(5-Chloropyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carbonyl]-amino}-cyclobutanecarbonyl)-amino]-2-ethoxy-phenyl}-acrylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Beaulieu PL, et al. J Med Chem. 2014 Dec 11;57(23):10130-43. 2. Beaulieu PL, et al. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1135-9. 3. Beaulieu PL, et al. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1140-5.
molnova catalog
related products
  • Ravidasvir

    Ravidasvir (PPI-668;BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay.

  • Beclabuvir

    Beclabuvir (BMS-791325) is a potent allosteric inhibitor of HCV NS5B polymerase with EC50 of 6 and 3 nM for genotype 1b and 1a in FRET assays, respectively.

  • Simeprevir

    A potent, orally available inhibitor of HCV NS3/4A protease with Ki of 0.36 nM, replicon EC50 of 7.8 nM.