Cart
sales@molnova.com
LLP2A
CAS No. 874148-50-2
LLP2A( —— )
Catalog No. M16358 CAS No. 874148-50-2
LLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameLLP2A
-
NoteResearch use only, not for human use.
-
Brief DescriptionLLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM.
-
DescriptionLLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM; shows no binding affinity for α2β1, α6β1, αLβ2 and αMβ2 integrins; can be used to image α4β1-expressing lymphomas with high sensitivity and specificity when conjugated to a near infrared fluorescent dye in a mouse xenograft model.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetIntegrin
-
RecptorIntegrin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number874148-50-2
-
Formula Weight810.953
-
Molecular FormulaC43H54N8O8
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name(S)-6-((1-carbamoylcyclohexyl)amino)-6-oxo-5-((S)-6-((E)-3-(pyridin-3-yl)acrylamido)-2-(2-(4-(3-(o-tolyl)ureido)phenyl)acetamido)hexanamido)hexanoic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Peng L, et al. Nat Chem Biol. 2006 Jul;2(7):381-9.
2. Beaino W, et al. J Nucl Med. 2014 Nov;55(11):1856-63.
3. Soodgupta D, et al. J Nucl Med. 2016 Apr;57(4):640-5.
molnova catalog
related products
-
RGD peptide GRGDNP
RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering.
-
Gambogic Acid
Gambogic Acid ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1.
-
OSU-T315
A novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 uM.
