RGD (Arg-Gly-Asp) Peptides
CAS No. 99896-85-2
RGD (Arg-Gly-Asp) Peptides( Arg-Gly-Asp | Arg Gly Asp | RGD )
Catalog No. M16919 CAS No. 99896-85-2
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 32 | In Stock |
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| 5MG | 51 | In Stock |
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| 10MG | 92 | In Stock |
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| 25MG | 147 | In Stock |
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| 50MG | 259 | In Stock |
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| 100MG | 406 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRGD (Arg-Gly-Asp) Peptides
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NoteResearch use only, not for human use.
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Brief DescriptionRGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
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DescriptionRGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
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In VitroRGD is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. There are 24 integrins binding to ECM molecules in a RGD dependent manner: α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1.
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In Vivo——
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SynonymsArg-Gly-Asp | Arg Gly Asp | RGD
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIntegrin
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number99896-85-2
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Formula Weight346.34
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Molecular FormulaC??H??N?O?
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Purity>98% (HPLC)
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SolubilityDMSO:<1 mg/mL;Ethanol:<1 mg/mL;Water:10 mg/mL (28.9 mM)
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SMILESO=C(O)C[C@@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)N)=O)=O
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Chemical NameArginylglycylaspartic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Lifitegrast sodium
Lifitegrast sodium (SAR-1118-023 sodium) is a small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), which reduces inflammation of the ocular surface, and may be used in the study of dry eye.
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BMS-688521
BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 (LFA-1), with potential anti-inflammatory activity.
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Abrilumab
Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin and can be used to study inflammatory bowel disease and ulcerative colitis.
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