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NOFD
CAS No. 856680-67-6
NOFD( N-oxalyl-d-phenylalanine )
Catalog No. M16212 CAS No. 856680-67-6
A specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameNOFD
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NoteResearch use only, not for human use.
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Brief DescriptionA specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM.
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DescriptionA specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM, but not HIF prolyl hydroxylase (>1 mM); also shows lack of in vitro inhibitory activities against a panel of Jumonji-C containing proteins KDM3A, KDM4E, and KDM6B (IC50>20 uM).
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In Vitro——
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In Vivo——
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SynonymsN-oxalyl-d-phenylalanine
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PathwayAngiogenesis
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TargetHIF/HIF Prolyl-hydroxylase
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RecptorHIF/HIF Prolyl-hydroxylase
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Research Area——
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Indication——
Chemical Information
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CAS Number856680-67-6
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Formula Weight237.211
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Molecular FormulaC11H11NO5
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-oxalyl-d-phenylalanine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. McDonough MA, et al. J Am Chem Soc. 2005 Jun 1;127(21):7680-1.
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