Cart
sales@molnova.com
NOFD
CAS No. 856680-67-6
NOFD( N-oxalyl-d-phenylalanine )
Catalog No. M16212 CAS No. 856680-67-6
A specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNOFD
-
NoteResearch use only, not for human use.
-
Brief DescriptionA specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM.
-
DescriptionA specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM, but not HIF prolyl hydroxylase (>1 mM); also shows lack of in vitro inhibitory activities against a panel of Jumonji-C containing proteins KDM3A, KDM4E, and KDM6B (IC50>20 uM).
-
In Vitro——
-
In Vivo——
-
SynonymsN-oxalyl-d-phenylalanine
-
PathwayAngiogenesis
-
TargetHIF/HIF Prolyl-hydroxylase
-
RecptorHIF/HIF Prolyl-hydroxylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number856680-67-6
-
Formula Weight237.211
-
Molecular FormulaC11H11NO5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameN-oxalyl-d-phenylalanine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. McDonough MA, et al. J Am Chem Soc. 2005 Jun 1;127(21):7680-1.
molnova catalog
related products
-
BMS202 hydrochloride...
PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM).
-
103D5R
103D5R is a small-molecule inhibitor of HIF-1α that displays an EC50 of 35 uM against hypoxia-induced alkaline phosphatase enzymatic reporter activity.
-
1,4-DPCA
1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 μM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH).
