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KRas-IN-1
CAS No. 84783-01-7
KRas-IN-1( MDK-3017 | MDK3017 | MDK 3017 | K-Ras-IN-2 | K-Ras Inhibitor-2 )
Catalog No. M16153 CAS No. 84783-01-7
A chemical fragment hit that binds to K-Ras (G12D) with affinities of 1.3-2 mM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
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| 5MG | 43 | In Stock |
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| 10MG | 68 | In Stock |
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| 25MG | 126 | In Stock |
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| 50MG | 194 | In Stock |
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| 100MG | 291 | In Stock |
|
| 200MG | 403 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKRas-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionA chemical fragment hit that binds to K-Ras (G12D) with affinities of 1.3-2 mM.
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DescriptionA chemical fragment hit that binds to K-Ras (G12D) with affinities of 1.3-2 mM; binds to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.
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In Vitro——
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In Vivo——
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SynonymsMDK-3017 | MDK3017 | MDK 3017 | K-Ras-IN-2 | K-Ras Inhibitor-2
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PathwayMAPK/ERK Signaling
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TargetRas
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RecptorRas
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number84783-01-7
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Formula Weight207.292
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Molecular FormulaC11H13NOS
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 28 mg/mL
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SMILESS=C(C1=CC=CC=C1O)N2CCCC2
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Chemical NameMethanethione, (2-hydroxyphenyl)-1-pyrrolidinyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sun Q, et al. Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6140-3.
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