Cart
sales@molnova.com
Mildronate
CAS No. 76144-81-5
Mildronate( Meldonium | Kvaterin | Mildronate | Quaterin )
Catalog No. M15892 CAS No. 76144-81-5
Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 37 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 86 | In Stock |
|
| 1G | 124 | In Stock |
|
Biological Information
-
Product NameMildronate
-
NoteResearch use only, not for human use.
-
Brief DescriptionMildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
-
DescriptionMildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
-
In VitroRT-PCR Cell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly decreased the mRNA expression of PFKP, PDK1, and PKM2 compared with the hypoxia group.Western Blot Analysis Cell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly reduced the protein expression of PFKP, PKM2, and LDHA.
-
In Vivo——
-
SynonymsMeldonium | Kvaterin | Mildronate | Quaterin
-
PathwayImmunology/Inflammation
-
TargetHydroxylase
-
RecptorDopamine β-hydroxylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number76144-81-5
-
Formula Weight146.19
-
Molecular FormulaC6H14N2O2
-
Purity>98% (HPLC)
-
SolubilitySoluble in Water
-
SMILESO=C([O-])CCN[N+](C)(C)C
-
Chemical Name3-(2,2,2-Trimethylhydrazine)propionate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zvejniece, L et al.Behavioral Pharmacology. 21: 548–555.
molnova catalog
related products
-
p-Ethynylphenylalani...
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a selective, effective, and reversible tryptophan hydroxylase (TPH) inhibitor, exhibits competitive inhibition with a Ki of 32.6 μM.
-
Ketoconazole
Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
-
Skimmin
Skimmin has anti-inflammatory activity, can significantly improve renal function and suppress the IgG deposition as well as the development of glomerular lesions in a rat model of membranous glomerulonephritis.
