Enalapril

Research use only, not for human use.

Enalapril is an angiotensin converting enzyme (ACE) inhibitor.

Enalapril is an angiotensin converting enzyme (ACE) inhibitor Target: ACE Enalapril belongs to a class of medications called angiotensin converting enzyme inhibitors. Normally angiotensin I is converted to angiotensin II by angiotensin converting enzyme (ACE).

Enalapril (10-20 μM) has an antiarrhythmic effect in ultrafiltered PV sleeve preparation isolated from canine hearts which can inhibit EAD and DAD-induced activity.Enalapril (50 μM, 24 hours) inhibits the induction of apoptosis by patient serum only when used prior to treatment of HUVEC with Alzheimer's disease (AD) serum.Pure Enalapril has better thermal stability than pure Enalapril. TApoptosis Analysis Cell Line:Human umbilical vein ECs (HUVECs)Concentration:50 μM Incubation Time:24 hours Result:Inhibited the induction of apoptosis by patient serum.

Enalapril (intraperitoneal injection, 0.03 mg/kg, once, 1 hour) reduces infarct volume due to middle cerebral artery occlusion and lower or higher doses are ineffective in Male NMRI mice. Animal Model:Male NMRI mice 20-40 g Dosage:0.03 mg/kg Administration:Intraperitoneal injection; once Result:Reduced the area of middle cerebral artery infarction in mice at 0.03 mg/kg.

Enalapril | Gadopril | Kinfil | Bonuten

Metabolic Enzyme/Protease

ACE

MRP1| ACE

Cardiovascular Disease

——

75847-73-3

376.45

C20H28N2O5

>98% (HPLC)

soluble in Water

O=C(O)[C@H]1N(C([C@H](C)N[C@H](C(OCC)=O)CCC2=CC=CC=C2)=O)CCC1

((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl-L-proline

(-20℃)

With Ice Pack

≥ 2 years