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OSU-03013
CAS No. 742112-34-1
OSU-03013( OSU 03013 | OSU03013 )
Catalog No. M15835 CAS No. 742112-34-1
OSU-03013 (OSU 03013, OSU03013) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameOSU-03013
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NoteResearch use only, not for human use.
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Brief DescriptionOSU-03013 (OSU 03013, OSU03013) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM.
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DescriptionOSU-03013 (OSU 03013, OSU03013) is a novel potent, orally active 3-phosphoinositide-dependent kinase-1 (PDK-1) with IC50 of 2 uM; induces apoptosis in PC-3 cells at low microM range, causes Akt dephosphorylation and inhibition of p70 S6 kinase activity; displays cytotocixity against a panel of 60 cell lines with mean GI50 of 3 uM.
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In Vitro——
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In Vivo——
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SynonymsOSU 03013 | OSU03013
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PathwayPI3K/Akt/mTOR signaling
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TargetPDK
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RecptorPDK
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Research Area——
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Indication——
Chemical Information
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CAS Number742112-34-1
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Formula Weight445.449
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Molecular FormulaC25H18F3N5
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Purity>98% (HPLC)
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Solubility——
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SMILESC1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)N=C(N)N)C(F)(F)F
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Chemical Name4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl-guanidine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Baryawno N, et al. Cancer Res. 2010 Jan 1;70(1):266-76.
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