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Sodium etidronate
CAS No. 7414-83-7
Sodium etidronate( Etidronic Acid | Didronel | HEDP | Hydroxyethylidene Diphosphonic Acid )
Catalog No. M15829 CAS No. 7414-83-7
A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 27 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSodium etidronate
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NoteResearch use only, not for human use.
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Brief DescriptionA diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
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DescriptionA diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover. (In Vitro):Etidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
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In VitroEtidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
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In Vivo——
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SynonymsEtidronic Acid | Didronel | HEDP | Hydroxyethylidene Diphosphonic Acid
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PathwayProteasome/Ubiquitin
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TargetTyrosinase
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Recptorprotein tyrosine phosphatase
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Research Area——
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Indication——
Chemical Information
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CAS Number7414-83-7
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Formula Weight249.99
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Molecular FormulaC2H6Na2O7P2
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Purity>98% (HPLC)
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SolubilityWater: 11.5 mg/mL
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SMILESCC(O)(P(O)(O)=O)P(O)(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Grases F, et al. Circ J. 2007 Jul; 71(7):1152-6.
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