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Oxantel Pamoate
CAS No. 68813-55-8
Oxantel Pamoate( —— )
Catalog No. M15628 CAS No. 68813-55-8
Oxantel pamoate is used as Antinematodal Agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 29 | In Stock |
|
| 500MG | 45 | In Stock |
|
| 1G | 65 | In Stock |
|
Biological Information
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Product NameOxantel Pamoate
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NoteResearch use only, not for human use.
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Brief DescriptionOxantel pamoate is used as Antinematodal Agent.
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DescriptionOxantel pamoate is used as Antinematodal Agent.(In Vivo):The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus.
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In Vitro——
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In VivoThe activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAntiparasitic
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number68813-55-8
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Formula Weight604.65
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Molecular FormulaC36H32N2O7
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESCN1CCCN=C1C=CC1=CC(O)=CC=C1.CN1CCCN=C1C=CC1=CC(O)=CC=C1.OC(=O)C1=C(CC2=C(C(O)=O)C(O)=CC3=CC=CC=C23)C2=CC=CC=C2C=C1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rim HJ, et al. Kisaengchunghak Chapchi. 1975 Dec;13(2):97-10
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