Escin
CAS No. 6805-41-0
Escin( —— )
Catalog No. M15597 CAS No. 6805-41-0
Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 35 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameEscin
-
NoteResearch use only, not for human use.
-
Brief DescriptionPentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
-
DescriptionPentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
-
In VitroWestern Blot Analysis Cell Line:OGD/R and rt-PA stimulated bEnd.3 cells Concentration:0.1, 0.5 and 1 μg/mL Incubation Time:24 h Result:Upregulated the expression of ZO-1 and Occludin.
-
In VivoAnimal Model:Con A-induced immune-mediated hepatitis mice Dosage:10 mg/kg Administration:p.o., 4 days Result:Decreased the peak activities of ALT (p?0.01), AST (p?0.001), and LDH.Ameliorated hepatic pathological abnormalities.Limited Con A-induced elevation in Ly6G-positive cell in liver.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number6805-41-0
-
Formula Weight1131.28
-
Molecular FormulaC55H86O24
-
Purity>98% (HPLC)
-
SolubilitySoluble in Water
-
SMILESCC=C(C)C(=O)OC1C([C@@]2(C(C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CCC([C@]5(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Yu Z, Su P. Pharmazie. 2013 Jun;68(6):428-30.
molnova catalog
related products
-
Argipressin
Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor V1 with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes respectively.
-
Tefludazine
Tefludazine, a novel neuroleptic with a benzindone structure, is a compound with good oral activity and antagonistic effects on dopamine and 5-hydroxytryptamine receptors.
-
DZ2002
DZ2002, an orally active, reversible, and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), exhibits significant immunosuppressive activity.
Cart
sales@molnova.com