Escin

CAS No. 6805-41-0

Escin( —— )

Catalog No. M15597 CAS No. 6805-41-0

Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Escin
  • Note
    Research use only, not for human use.
  • Brief Description
    Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
  • Description
    Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
  • In Vitro
    Western Blot Analysis Cell Line:OGD/R and rt-PA stimulated bEnd.3 cells Concentration:0.1, 0.5 and 1 μg/mL Incubation Time:24 h Result:Upregulated the expression of ZO-1 and Occludin.
  • In Vivo
    Animal Model:Con A-induced immune-mediated hepatitis mice Dosage:10 mg/kg Administration:p.o., 4 days Result:Decreased the peak activities of ALT (p?
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    6805-41-0
  • Formula Weight
    1131.28
  • Molecular Formula
    C55H86O24
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in Water
  • SMILES
    CC=C(C)C(=O)OC1C([C@@]2(C(C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CCC([C@]5(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yu Z, Su P. Pharmazie. 2013 Jun;68(6):428-30.
molnova catalog
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