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Nutlin-3b
CAS No. 675576-97-3
Nutlin-3b( Nutlin 3b )
Catalog No. M15581 CAS No. 675576-97-3
A p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 56 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 79 | In Stock |
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| 25MG | 153 | In Stock |
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| 50MG | 249 | In Stock |
|
| 100MG | 360 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNutlin-3b
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NoteResearch use only, not for human use.
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Brief DescriptionA p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM.
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DescriptionA p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
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In Vitro——
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In Vivo——
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SynonymsNutlin 3b
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PathwayApoptosis
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TargetMDM2-p53
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RecptorMdm2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number675576-97-3
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Formula Weight581.4896
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Molecular FormulaC30H30Cl2N4O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESClC1=CC=C([C@H]2[C@@H](C3=CC=C(Cl)C=C3)N=C(C4=CC=C(OC)C=C4OC(C)C)N2C(N5CCN([H])C(C5)=O)=O)C=C1
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Chemical Name2-Piperazinone, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Vassilev LT, et al. Science, 2004, 303(5659), 844-848.
molnova catalog
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p53 17-26
This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2.
