Nitrofurantoin( NSC 2107 | NSC 44150 )

Catalog No. M15565 CAS No. 67-20-9

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HNMR

HPLC

MSDS

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Product Name

Nitrofurantoin
Note

Research use only, not for human use.
Brief Description

Nitrofurantoin is an antibiotic usually used to treat urinary tract infections.
Description

Nitrofurantoin is an antibiotic usually used to treat urinary tract infections.(In Vitro):Nitrofurantoin (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates.
In Vitro

Nitrofurantoin (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates. Cell Viability Assay Cell Line:E. coli isolates: DA10708, DA13815, DA13824, DA13957, DA13992, DA10626, DA10627 Concentration:0, 32, 64, 128, 256, and 512 mg/L Incubation Time:8 hours Result:Observed bactericidal effect at 32 mg/L For DA10708, DA13815 and DA13824.Inhibited the growth of DA13957 and DA13992 completely at 128 mg/L, observed bactericidal effect at 256 mg/L.Showed a moderate killing at >128 mg/L for DA10626 and DA10627.
In Vivo

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Synonyms

NSC 2107 | NSC 44150
Pathway

Membrane Transporter/Ion Channel
Target

NADPH
Recptor

NADPH nitroreductase
Research Area

Infection
Indication

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CAS Number

67-20-9
Formula Weight

238.16
Molecular Formula

C8H6N4O5
Purity

>98% (HPLC)
Solubility

Water: 79 mg/l at 24 °C
SMILES

O=C(N1)CN(/N=C/C2=CC=C([N+]([O-])=O)O2)C1=O
Chemical Name

(E)-1-(((5-nitrofuran-2-yl)methylene)amino)imidazolidine-2,4-dione

1. Sisson G, et al. Antimicrob Agents ChemOthers. 2002 Jul;46(7):2116-23.

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