Iohexol( Iohexol, Omnipaque, Exypaque, Accudenz, Histodenz, Nycodenz )

Catalog No. M15517 CAS No. 66108-95-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Iohexol
Note

Research use only, not for human use.
Brief Description

Iohexol is a contrast agent. Target: Others Iohexol is a contrast agent.
Description

Iohexol is a contrast agent. Target: Others Iohexol is a contrast agent. The osmolality of iohexol ranges from 322 mOsm/kg-approximately 1.1 times that of blood plasma-to 844 mOsm/kg, almost three times that of blood.
In Vitro

Cell Viability Assay Cell Line:NRK 52-E Concentration:150 mg I/mL Incubation Time:0-24 h Result:Reduced the MTT conversion at 12 and 24 h.Inhibited mitochondrial dehydrogenase activity at 12 and 24 h.
In Vivo

Animal Model:Healthy dogs Dosage:0.25-4 mL/kg Administration:Oral gavage (p.o.), weekly Result:Peaked the iohexol serum concentrations between 2 and 4 hours.Reduced radiolucency after application of 0.25 mL/kg and 4 mL/kg.Included watery diarrhea after ingestion of 4 mL/kg.
Synonyms

Iohexol, Omnipaque, Exypaque, Accudenz, Histodenz, Nycodenz
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

——

CAS Number

66108-95-0
Formula Weight

821.14
Molecular Formula

C19H26I3N3O9
Purity

>98% (HPLC)
Solubility

Soluble in DMSO
SMILES

CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Name

N1,N3-bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide

1. Yin Q, et al. J Am Chem Soc. 2013 Sep 18; 135(37):13620-3.

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