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AZD3759 hydrochloride
CAS No. 1626387-81-2
AZD3759 hydrochloride( —— )
Catalog No. M18097 CAS No. 1626387-81-2
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 45 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 39 | In Stock |
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| 10MG | 56 | In Stock |
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| 25MG | 96 | In Stock |
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| 50MG | 166 | In Stock |
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| 100MG | 274 | In Stock |
|
| 200MG | 398 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZD3759 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionAZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor.
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DescriptionAZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorEGFR (exon 19De)| EGFR (L858R)| EGFR (wt)
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Research Area——
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Indication——
Chemical Information
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CAS Number1626387-81-2
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Formula Weight496.36
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Molecular FormulaC22H24Cl2FN5O3
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@@H]1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zeng Q, et al. J Med Chem. 2015 Oct 22;58(20):8200-15.
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