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4|-Demethylepipodophyllotoxin
4|-Demethylepipodophyllotoxin
CAS No. 6559-91-7
4|-Demethylepipodophyllotoxin( —— )
Catalog No. M15493 CAS No. 6559-91-7
A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 27 | In Stock |
|
Biological Information
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Product Name4|-Demethylepipodophyllotoxin
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NoteResearch use only, not for human use.
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Brief DescriptionA potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
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DescriptionA potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorTopoII
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number6559-91-7
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Formula Weight400.3787
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Molecular FormulaC21H20O8
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C1OC[C@]2([H])[C@H](O)C3=C(C=C4OCOC4=C3)[C@@H](C5=CC(OC)=C(O)C(OC)=C5)[C@]21[H]
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Chemical NameFuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR,9S)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dhawan D, et al. Carcinogenesis. 1999 Jun;20(6):997-1003.
2. Gewirtz DA. Cancer Res. 1985 Dec;45(12 Pt 1):6290-2.
3. Lee KH, et al. J Med Chem. 1990 May;33(5):1364-8.
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