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Home - Products - Cytoskeleton/Cell Adhesion Molecules - Microtubule/Tubulin - 4|-Demethylepipodophyllotoxin

4|-Demethylepipodophyllotoxin

CAS No. 6559-91-7

4|-Demethylepipodophyllotoxin( —— )

Catalog No. M15493 CAS No. 6559-91-7

A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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1 mL x 10 mM in DMSO 28 In Stock
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Biological Information

  • Product Name
    4|-Demethylepipodophyllotoxin
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
  • Description
    A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    TopoII
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    6559-91-7
  • Formula Weight
    400.3787
  • Molecular Formula
    C21H20O8
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C1OC[C@]2([H])[C@H](O)C3=C(C=C4OCOC4=C3)[C@@H](C5=CC(OC)=C(O)C(OC)=C5)[C@]21[H]
  • Chemical Name
    Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR,9S)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dhawan D, et al. Carcinogenesis. 1999 Jun;20(6):997-1003. 2. Gewirtz DA. Cancer Res. 1985 Dec;45(12 Pt 1):6290-2. 3. Lee KH, et al. J Med Chem. 1990 May;33(5):1364-8.
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