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Auristatin E

CAS No. 160800-57-7

Auristatin E( —— )

Catalog No. M26615 CAS No. 160800-57-7

Auristatin E inhibits cell division by blocking the polymerisation of tubulin. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Auristatin E
  • Note
    Research use only, not for human use.
  • Brief Description
    Auristatin E inhibits cell division by blocking the polymerisation of tubulin. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity.
  • Description
    Auristatin E inhibits cell division by blocking the polymerisation of tubulin. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Auristatin E, an MMAE analog, is cytotoxin in Antibody-drug conjugates.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    160800-57-7
  • Formula Weight
    732.02
  • Molecular Formula
    C40H69N5O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (136.61 mM)
  • SMILES
    [H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Melo KM, et al. Short-term exposure to low doses of rotenone induces developmental, biochemical, behavioral, and histological changes in fish. Environ Sci Pollut Res Int. 2015 Sep;22(18):13926-38.
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