Nisoldipine
CAS No. 63675-72-9
Nisoldipine( BAY-k 5552 )
Catalog No. M15415 CAS No. 63675-72-9
A dihydropyridine type calcium channel blocker that is used as an antihypertensive.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 32 | In Stock |
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| 500MG | 41 | In Stock |
|
| 1G | 65 | In Stock |
|
Biological Information
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Product NameNisoldipine
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NoteResearch use only, not for human use.
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Brief DescriptionA dihydropyridine type calcium channel blocker that is used as an antihypertensive.
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DescriptionA dihydropyridine type calcium channel blocker that is used as an antihypertensive.Hypertension Approved.
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In Vitro——
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In Vivo——
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SynonymsBAY-k 5552
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorL-typeCav1.2
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Research AreaCardiovascular Disease
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IndicationHypertension
Chemical Information
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CAS Number63675-72-9
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Formula Weight388.4144
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Molecular FormulaC20H24N2O6
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
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Chemical Name3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, 3-methyl 5-(2-methylpropyl) ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Upacicalcet
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.
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Yangambin
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests.
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Gallopamil
Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM.
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