Physostigmine Salicylate

CAS No. 57-64-7

Physostigmine Salicylate( —— )

Catalog No. M15104 CAS No. 57-64-7

Physostigmine is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 82 In Stock
2MG 46 In Stock
5MG 75 In Stock
10MG 103 In Stock
25MG 180 In Stock
50MG 247 In Stock
100MG 338 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Physostigmine Salicylate
  • Note
    Research use only, not for human use.
  • Brief Description
    Physostigmine is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor.
  • Description
    Physostigmine is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean.(In Vivo):Physostigmine salicylate (Eserine salicylate; 0.03-0.3 mg/kg; s.c.; daily for 6 weeks) improves deficits in contextual and cued memory in Tg(+) mice.Physostigmine salicylate (IV; 0.1, 0.2 mg/kg) delays time to emergence from isoflurane anesthesia at doses ≥0.2 mg/kg in male Sprague-Dawley rats.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Heterozygous transgenic mice (Tg(+) mice)Dosage:0.03, 0.1, and 0.3 mg/kg Administration:SC; daily for 6 weeks Result:Tended to normalize the contextual memory deficit in Tg(+) animals so that they became more similar to Tg(-) animals.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    57-64-7
  • Formula Weight
    413.48
  • Molecular Formula
    C22H27N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C.C1=CC=C(C(=C1)C(=O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lim DK, et al. Pharmacol Biochem Behav. 1988 Nov;31(3):627-3
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