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CGS 15943
CAS No. 104615-18-1
CGS 15943( —— )
Catalog No. M23255 CAS No. 104615-18-1
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 75 | In Stock |
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| 25MG | 150 | In Stock |
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| 50MG | 230 | In Stock |
|
| 100MG | 346 | In Stock |
|
| 200MG | 510 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCGS 15943
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NoteResearch use only, not for human use.
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Brief DescriptionCGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.
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DescriptionCGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively.
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In VitroCell Viability Assay Cell Line:HLF, SK-Hep-1, HepG2 and PLC-PRF-5 cells Concentration:0 μM; 1 μM; 5 μM; 10 μM; 20 μM Incubation Time:24 hours Result:Inhibited growth of four distinct HCC cell lines.Western Blot Analysis Cell Line:HLF and Sk-Hep-1 cells Concentration:0 μM; 1 μM; 5 μM; 10 μM; 20 μM Incubation Time:24 hours Result:Inhibited the PI3K/Akt pathway in HLF and Sk-Hep-1 cells
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorAdenosine A1?receptor|adenosine A2A receptor|adenosine A2B receptor|adenosine A3 receptor|p110γ|p110δ
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Research Area——
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Indication——
Chemical Information
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CAS Number104615-18-1
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Formula Weight285.69
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Molecular FormulaC13H8ClN5O
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Purity>98% (HPLC)
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SolubilityDMSO:12.22 mg/mL (42.77 mM; Need ultrasonic)
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SMILESC1=COC(=C1)C2=NN3C(=N2)C4=C(C=CC(=C4)Cl)N=C3N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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4-Hydroxycoumarin, a coumarin derivative.4-Hydroxycoumarin serves as an immediate precursor of 4-hydroxycoumarin (4HC) type anticoagulants (for example, warfarin).?4-Hydroxycoumarin derivatives ?are employed as the anticoagulant, antibacterial, antifungal, antiviral, antitumor, antiprotozoal, insecticidal, antimycobacterial, antimutagenic, antioxidant, anti-inflammatory agents, HIV protease inhibitors and tyrosine kinase inhibitors.
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PNU 282987
PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).
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Acetamiprid
Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. Acetamiprid decreases in body weight and mildly affected spermatogenesis.
