Cart
sales@molnova.com
ISRIB
CAS No. 548470-11-7
ISRIB( —— )
Catalog No. M14973 CAS No. 548470-11-7
ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 83 | In Stock |
|
| 5MG | 46 | In Stock |
|
| 10MG | 74 | In Stock |
|
| 25MG | 149 | In Stock |
|
| 50MG | 246 | In Stock |
|
| 100MG | 362 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameISRIB
-
NoteResearch use only, not for human use.
-
Brief DescriptionISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
-
DescriptionISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMAPK/ERK Signaling
-
TargetERK
-
RecptorPERK
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number548470-11-7
-
Formula Weight451.34
-
Molecular FormulaC22H24Cl2N2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM
-
SMILESClC1=CC=C(OCC(=O)NC2CCC(CC2)NC(=O)COC2=CC=C(Cl)C=C2)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sidrauski C, et al. Elife. 2013, 2, e00498.
molnova catalog
related products
-
ERα degrader-2
ERα degrader-2 is a selective and potent estrogen receptor (SERD) degrader with anticancer activity, exhibiting an EC50 value of 0.3 nM for ERα degradation.
-
AZ32
AZ32 is an orally bioavailable and blood-brain barrier-penetrating?ATM?inhibitor with an?IC50?of <6.2 nM for ATM enzyme, and an?IC50?of 0.31 μM for ATM in cell.
-
Gardenin A
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
